Chinese researchers have made a significant breakthrough in wound healing technology by developing a band-aid-like biodegradable composite material that promotes complete skin regeneration. The innovative material not only accelerates the healing process but also facilitates the growth of skin with normal sensory functions such as touch and pain perception.
The study, a collaboration between Zhongnan Hospital of Wuhan University and Wuhan University of Technology, was recently published in the International Journal of Biological Macromolecules. The biocomposite material is crafted from natural polymers including silk fibroin and sodium alginate. When applied to a wound, its unique micro-nano layered structure guides skin cells to migrate across various skin layers, fostering full-thickness skin repair and regeneration.
“Our material acts as a scaffold that directs skin cells to ‘climb’ and fill in the wound, resulting in the formation of native-like skin,” explained Professor Wang Xinyu of Wuhan University of Technology. Unlike artificial skin, the regenerated skin possesses normal sensory functions, enhancing the quality of healing.
An added advantage of this material is its biodegradability. It can be absorbed by the human body or metabolized into harmless byproducts such as amino acids, carbon dioxide, and water. This eliminates the need for surgical removal and reduces the risk of allergic reactions associated with non-degradable materials.
The potential applications of this breakthrough extend to the repair of skin and mucosal defects in the oral and maxillofacial regions, as well as treating burn-induced skin injuries. It addresses critical issues such as the shortage of autologous skin graft materials, providing a promising alternative for medical professionals and patients alike.
Reference(s):
Researchers develop biodegradable material for enhanced wound healing
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