In a novel approach to combat Alzheimer’s disease, Chinese medical researchers are investigating an experimental neck surgery that could help clear toxic brain proteins linked to dementia. Over 17 million people in China live with Alzheimer’s or related disorders, highlighting the urgency for innovative treatments.
A Surgical Surprise
Originally designed to treat lymphatic blockages, deep cervical lymphovenous anastomosis (dcLVA) is now being repurposed by Dr. Xie Qingping, a microsurgery specialist in Hangzhou. Since 2020, the procedure—which reroutes blocked lymphatic vessels in the neck to veins—has been performed on over 600 patients. Preliminary results suggest 80% experienced improved cognition or behavioral symptoms.
Connecting the Dots
The discovery began in 2019 when Dr. Xie treated a patient with chronic tinnitus. Observing abnormal neck lymphatics, he applied his expertise in LVA to ease blockages. Post-surgery, the patient reported clearer vision and reduced brain fog. "This hinted at a link between cervical lymphatic drainage and central nervous system detoxification," Xie explained.
Later, Xie’s findings aligned with U.S. research on brain "plumbing" systems that flush toxins like amyloid-beta, a hallmark of Alzheimer’s. This cross-continental insight has bolstered hopes for addressing the disease’s root causes.
Cautious Optimism
While initial outcomes are promising, experts stress the need for rigorous trials. Surgery risks and long-term efficacy remain uncertain. Still, the approach offers a glimmer of hope for advanced-stage patients with limited options.
Reference(s):
Neck surgery raises hope for Alzheimer's patients: What to know
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