China’s Ministry of Science and Technology has announced new ethical guidelines to regulate human genome editing research, aiming to promote responsible innovation in this groundbreaking field.
The guidelines emphasize that human genome editing research should adhere to principles that prioritize human well-being, respect individual rights, exercise prudence and responsibility, ensure fairness and justice, and maintain openness and transparency.
“The use of human genome editing technology in research must be carefully assessed, taking into full consideration its scientific and social value, as well as potential risks,” the guidelines state.
In the realm of clinical research, the guidelines stress the importance of thoroughly evaluating the severity of diseases and potential risks to patients. It calls for a delicate balance between advancing medical science and safeguarding human health.
Significantly, the guidelines strictly prohibit the use of edited germ cells, fertilized eggs, or embryos for pregnancy and reproduction. “Currently, any clinical research involving germline genome editing is irresponsible and not allowed,” the document asserts.
The path to clinical research is outlined with stringent conditions: it can only proceed when benefits, risks, and alternative options are fully understood and carefully weighed. Additionally, safety and effectiveness issues must be addressed, and there must be broad social consensus, rigorous evaluation, and strict supervision in place.
Furthermore, the guidelines set general requirements for human genome editing research. These include establishing reasonable objectives, protecting research participants, possessing the necessary qualifications and resources, and obtaining informed consent from participants.
Special provisions are also made for handling leftover biological samples and stipulate conditions for using somatic cell genome editing strategies at various stages of research, including basic, preclinical, and clinical research phases.
The publication of these guidelines reflects the Chinese mainland’s commitment to fostering ethical practices in cutting-edge scientific research, ensuring that advancements in genome editing are pursued responsibly and with due regard for humanity’s collective well-being.
Reference(s):
China publishes ethical guidelines for human genome editing research
cgtn.com
