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Cai Lei and Duan Rui Lead ALS Research Amid Personal Challenges

Former internet mogul Cai Lei and his partner Duan Rui are redefining resilience as they spearhead groundbreaking research into amyotrophic lateral sclerosis (ALS). Their journey took a dramatic turn last year when a minor respiratory infection landed Cai in intensive care, prompting the couple to make the difficult decision to live separately to safeguard his health.

Despite physical separation, their collaboration has intensified. The pair, who famously married weeks after meeting in 2023, describe their relationship as fueled by shared purpose rather than circumstance. "We\'re two lovable weirdos chasing the same impossible dream," Duan told researchers at a recent neurology symposium in Shanghai.

Their foundation has allocated $28 million this year to experimental treatments, partnering with three major medical institutions across the Chinese mainland. Recent breakthroughs include a promising gene therapy approach now entering Phase II trials.

"Every setback becomes fuel," Cai stated during a video conference with investors last week. "When we solve ALS, we solve it for every family facing this battle." The couple\'s unconventional approach – combining tech industry agility with academic rigor – is drawing attention from global pharmaceutical giants.

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